Nitric oxide and electrogenic metals (Ca, Na, K) in epidermal cells
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چکیده
منابع مشابه
Na-Ca or Na-Ca-K exchange in rod photoreceptors.
Remarkably dynamic Ca z ÷ fluxes control Ca 2 ÷ homeostasis in the outer segments of vertebrate rod photoreceptors (ROS). Ca 2 ÷ fluxes are believed to be carried by only two different membrane proteins embedded in the ROS plasma membrane; these two proteins as well as some of the other main molecular components of ROS are schematically depicted in Fig. 1. ROS are the sites of the process of vi...
متن کاملNitric oxide activates PKCα and inhibits Na+-K+-ATPase in opossum kidney cells.
Nitric oxide (NO) reduces the molecular activity of Na+-K+-ATPase in opossum kidney (OK) cells, a proximal tubule cell line. In the present study, we investigated the cellular mechanisms for the inhibitory effect of NO on Na+-K+-ATPase. Sodium nitroprusside (SNP), a NO donor, inhibited Na+-K+-ATPase in OK cells, but not in LLC-PK1cells, another proximal tubule cell line. Similarly, phorbol 12-m...
متن کاملNa/Ca Exchange Facilitates Ca-dependent Activation of Endothelial Nitric-oxide Synthase*
Recent evidence suggests the expression of a Na/ Ca exchanger (NCX) in vascular endothelial cells. To elucidate the functional role of endothelial NCX, we studied Ca signaling and Ca-dependent activation of endothelial nitric-oxide synthase (eNOS) at normal, physiological Na gradients and after loading of endothelial cells with Na ions using the ionophore monensin. Monensin-induced Na loading m...
متن کاملNa(+)/Ca(2+) exchange facilitates Ca(2+)-dependent activation of endothelial nitric-oxide synthase.
Recent evidence suggests the expression of a Na(+)/Ca(2+) exchanger (NCX) in vascular endothelial cells. To elucidate the functional role of endothelial NCX, we studied Ca(2+) signaling and Ca(2+)-dependent activation of endothelial nitric-oxide synthase (eNOS) at normal, physiological Na(+) gradients and after loading of endothelial cells with Na(+) ions using the ionophore monensin. Monensin-...
متن کامل"Creep currents" in single frog atrial cells may be generated by electrogenic Na/Ca exchange
The objective of these experiments was to test the hypothesis that the "creep currents" induced by Na loading of single frog atrial cells (Hume, J. R., and A. Uehara. 1986. Journal of General Physiology. 87:833) may be generated by an electrogenic Na/Ca exchanger. Creep currents induced by Na loading were examined over a wide range of membrane potentials. During depolarizing voltage-clamp pulse...
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ژورنال
عنوان ژورنال: Biomeditsinskaya Khimiya
سال: 2015
ISSN: 2310-6905,2310-6972
DOI: 10.18097/pbmc20156104503